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ChemicalBook Product Catalog API Antibiotics Other antibiotic Drugs Posaconazole

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Posaconazole

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No171228-49-2
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

6YR

China

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Chemical Properties

Product Name	Posaconazole
CAS No	171228-49-2
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Tetracycline Basic information

Product Name:	Tetracycline
Synonyms:	12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;abricycline;achromycin(naphthacenederivative);achromycin(naphthracenederivatives)
CAS:	60-54-8
MF:	C22H24N2O8
MW:	444.44
EINECS:	200-481-9
Product Categories:	Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Peptide Synthesis/Antibiotics;Inhibitors
Mol File:	60-54-8.mol

Tetracycline Chemical Properties

Melting point	175-177 °C(lit.)
alpha	D25 -257.9° (0.1N HCl); D25 -239° (methanol)
Boiling point	554.44°C (rough estimate)
density	1.3809 (rough estimate)
refractive index	1.6500 (estimate)
storage temp.	2-8°C
solubility	95% ethanol: soluble12.5mg/mL
pka	pKa (50% aq DMF): 8.3, 10.2(at 25℃)
color	yellow to yellow orange
Water Solubility	Limited solubility in water. Soluble in 1M HCl with heating.
Merck	13,9271
CAS DataBase Reference	60-54-8(CAS DataBase Reference)
NIST Chemistry Reference	Tetracycline(60-54-8)
EPA Substance Registry System	2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-(60-54-8)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38
Safety Statements	22-36-26
WGK Germany	3
RTECS	QI8750000
F	3-8-10
HS Code	29413000
Hazardous Substances Data	60-54-8(Hazardous Substances Data)
Toxicity	LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal)

Tetracycline Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	antibactierial
Uses	antibacterial, antiamebic, antirickettsial
Uses	Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products.
Uses	Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
Uses	Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial

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