Docetaxel trihydrate

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career henan chemical co

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China

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Docetaxel trihydrate Basic information

Product Name:	Docetaxel trihydrate
Synonyms:	DOCETAXEL HYDRATE;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.;Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyc;Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester trihydrate, [2aR-[2aα,4β,4aβ,6β,9α(αR,βS),11α,12α,12aα,12bα]]-;Docetaxel trihydrate;Benzenepropanoic acid, beta-(((1,1-dimethylethoxy)carbonyl)amino)-alpha-hydroxy-, (2ar,4S,4as,6R,9S,11S,12S,12ar,12bs)-12B-(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,6,11-trihydroxy-4A,8,1313-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-yl ester, trihydrate, (alphar,betas)-;Unii-15H5577cqd;Xrp6976
CAS:	148408-66-6
MF:	C43H53NO14.3H2O
MW:	861.929
EINECS:	1308068-626-2
Product Categories:	All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Plant extract;Plant extracts;Herb extract;TAXOTERE;Anti-cancer&immunity;Anticancer
Mol File:	148408-66-6.mol

Docetaxel trihydrate Chemical Properties

Melting point	186-192°C
InChIKey	XCDIRYDKECHIPE-KHDBCEGQSA-N
CAS DataBase Reference	148408-66-6(CAS DataBase Reference)

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MSDS Information

Docetaxel trihydrate Usage And Synthesis

Chemical Properties	White Crystalline Powder
Uses	An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin
Definition	ChEBI: The trihydrate form of docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.

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