Chinese name: O-aminobenzamide
English name: Anthranilamide
Alias: O-aminobenzamide
English alias: ATA
CAS: 88-68-6
EINECS: 201-851-2
Chemical formula: C7H8N2O
Molecular weight: 136.15
InChI InChI = 1 / C7H8N2O/c8-6-4-2-6-4-2 (6) 7 (9) 10 / h1-4 h, 8 H2, (H2, 9, 10)
InChIKey PXBFMLJZNCDSMP-UHFFFAOYSA-N
Density: 1.1778 (rough estimate)
Melting point: 111-113 °C (lit.)
Boiling point: 300 °C
Flash point: 198 °C
water solubility: Soluble in hot water and alcohol. Slightly soluble in ether and benzene. Very soluble in ethyl acetate.
Steam pressure: 0.001Pa at 20℃
Solubility: < 5g/l
Refractive index: 1.5460 (estimate)
Acidity coefficient: 15.77±0.50(Predicted)
Storage conditions: Keep in dark place,Inert atmosphere,Room temperature
Appearance: crystalline powder or sheet
Color: Light brown to gray-brown
BRN 508509
MDL number: MFCD00007981
Water solubility: < 5 g/l (20°C) Ethanol solubility: 140 g/l (20°C), slightly soluble in ether, benzene.
Purpose:
-o-aminobenzamide is commonly used as an important intermediate in organic synthesis.
- It is an important raw material for the preparation of metal complexes such as bis (o-aminobenzamide) copper;
- Widely used in dyes, cosmetics and other fields.
Preparation:
A common way to prepare anthranilide is through the reaction of benzoic acid and aniline:
1. Firstly, benzoic acid and aniline were added into the reaction bottle with molar ratio of 1:1;
2. Heat the reaction bottle, the reaction temperature is usually between 180-190 degrees Celsius;
3. Continuous stirring and heating, which usually takes several hours;
4. After the reaction, the reaction liquid is cooled and crystallized to obtain pure o-aminobenzamide.
China
