Basic information Description Generic formulation Indications Dose titration Cautions Interactions Special populations Behavioural and cognitive effects in patients with epilepsy Psychiatric use Safety Related Supplier

ChemicalBook Product Catalog API Nervous system drugs Antiepileptic and anticonvulsant Gabapentin hydrochloride

1/1

Gabapentin hydrochloride

$ 260.00 /1KG

Min. Order1KG
Purity99%
Cas No60142-96-3
Supply Ability1000
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Gabapentin hydrochloride
CAS No	60142-96-3
EC-No	262-076-3
Min. Order	1KG
Purity	99%
Supply Ability	1000
Release date	2019/07/06

CR315

Product Name:	Gabapentin hydrochloride
Synonyms:	NEURONTIN;GABAPENTINE;GABAPENTIN HYDROCHLORIDE;GABAPENTIN;GOE-3450;(1-AMINOMETHYL-CYCLOHEXYL)-ACETIC ACID;1-(AMINOMETHYL)CYCLOHEXANEACETIC ACID;AKOS 92109
CAS:	60142-96-3
MF:	C9H17NO2
MW:	171.24
EINECS:	262-076-3
Product Categories:	Organic acids;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's;GABA/Glycine receptor;Ion channels;API;ABILIFY;Other APIs;Pharmaceutical raw materials;Miscellaneous Biochemicals
Mol File:	60142-96-3.mol

Gabapentin hydrochloride Chemical Properties

Melting point	162°C
Fp	9℃
storage temp.	Desiccate at +4°C
solubility	H₂O: 10 mg/mL
form	solid
pka	pKa1 (25°) 3.68; pKa2 10.70
color	off-white
Merck	14,4319
CAS DataBase Reference	60142-96-3(CAS DataBase Reference)

Safety Information

Hazard Codes	T,Xi,F
Risk Statements	61-36/37/38-39/23/24/25-23/24/25-11
Safety Statements	53-26-36/37/39-45-36-36/37-16
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3
RTECS	GU6496000
HazardClass	IRRITANT
Hazardous Substances Data	60142-96-3(Hazardous Substances Data)

MSDS Information

Provider	Language
1-(Aminomethyl)cyclohexaneacetic acid	English
SigmaAldrich	English

Gabapentin hydrochloride Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	Amino acid structurally related to -Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant
Uses	Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.
Uses	antipsychotic, 5HT2A antagonist
Uses	selective H1-receptor antagonist
Uses	For the treatment of adult Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
Definition	ChEBI: A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Biological Activity	Anticonvulsant with several possible mechanisms of action. Increases GABA in the brain and binds to a novel site associated with voltage-sensitive Ca 2+ channels. Prevents neuronal death and is antinociceptive and anxiolytic.

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