Product Name:	Afatinib
Synonyms:	Afatinib;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dime;Afatinib API;Afatinib(BIBW2992MA2);Afatinib (with 1 int.)
CAS:	850140-72-6
MF:	C24H25ClFN5O3
MW:	485.9384032
EINECS:
Product Categories:	Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;tyrosine kinase receptor inhibitor;Antineoplastic;Afatinib
Mol File:	850140-72-6.mol

Uses	An aminocrotonylamino-substituted quinazoline derivative
Definition	ChEBI: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its di aleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer.

Afatinib

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