Product Name | ferulic acid |
CAS No | 1135-24-6 |
EC-No | |
Min. Order | 10G |
Purity | 99% |
Supply Ability | 1000kg |
Release date | 2018/10/22 |
Ferulic Acid Basic information |
Plant sources Physical and Chemical Properties Lipid-Lowering effect Antimicrobial effect Food Industry Applications Pharmacological effects Synthetic method Uses |
Product Name: | Ferulic Acid |
Synonyms: | 3-(4-hydroxy-3-methoxyphenyl)-2-Propenoic acid 4-Hydroxy-3-methoxycinnamic acid;AKOS BBS-00006472;3-METHOXY-4-HYDROXYCINNAMIC ACID;4-HYDROXY-3-METHOXYCINNAMIC ACID;3-(4-HYDROXY-3-METHOXYPHENYL)ACRYLIC ACID;(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)ACRYLIC ACID;AURORA 17401;BUTTPARK 121\04-54 |
CAS: | 1135-24-6 |
MF: | C10H10O4 |
MW: | 194.18 |
EINECS: | 208-679-7 |
Product Categories: | Inhibitors;FINE Chemical & INTERMEDIATES;Aromatic Cinnamic Acids, Esters and Derivatives;Aromatics;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product |
Mol File: | 1135-24-6.mol |
Ferulic Acid Chemical Properties |
Melting point | 168-172 °C(lit.) |
density | 1.316(20.0000℃) |
storage temp. | -20°C Freezer |
form | powder |
color | slightly yellow |
Water Solubility | soluble |
InChIKey | KSEBMYQBYZTDHS-HWKANZROSA-N |
CAS DataBase Reference | 1135-24-6(CAS DataBase Reference) |
NIST Chemistry Reference | Cinnamic acid, 4-hydroxy-3-methoxy-(1135-24-6) |
EPA Substance Registry System | 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)- (1135-24-6) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
RTECS | UD3365500 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
HS Code | 29162090 |
Hazardous Substances Data | 1135-24-6(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
3-(4-Hydroxy-3-methoxyphenyl)acrylic acid | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
Ferulic Acid Usage And Synthesis |
Plant sources | Ferulic acid is a kind of phenolic acid extracted from the resin of ferula asafetida. Ferula asafetida is a kind of Umbelliferae perennial herb with a strong garlic smell and living in sandy areas. It is mainly produced in Xinjiang. During the nascent stage, there are only root leaves. At 5 years, scape emerges. The scape is very strong with its height being up to two meters. At end spring and early summer (flowering stage to early fruit stage), apply slanting cut from the upper position down to the bottom separately, collect oozing milky resin, dry it. Ferula asafetida contains volatile oils, gums and resins with oil containing various kinds of organic acids such as (R)-sec-butyl-1-propenyl disulfide, 1(1-methylthio-propyl) 1-propenyl disulfide, sec-butyl 3-methylthio-allyl-disulfide. Resin containing ferulic acid and its related esters. Figure 1 is Resina Ferulae |
Physical and Chemical Properties | Ferulic acid is an aromatic acid widely being presented in plant kingdom and is the components of suberin. It amount is very small presented in plants in its free state but with its main form in forming bound state with oligosaccharides, polyamines, lipids and polysaccharides. It has many health functions, such as free radical scavenging, anti-thrombotic, anti-inflammatory, anti-tumor, prevention and treatment of hypertension, heart disease, and enhanced sperm activity and so on. Ferulic acid has a low toxicity and is easy for being metabolized by human. It can be used as a food preservative and has a wide range of applications in the field of food and medication. The above information is edited by the chemicalbook of Yan Yanyong. |
Lipid-Lowering effect | Ferulic acid can competitively inhibit the liver mevalonate-5-pyrophosphate dehydrogenase activity, inhibiting the synthesis of cholesterol in the liver, so as to achieve the purpose of lowering blood pressure. |
Antimicrobial effect | Ferulic acid exhibits a broader anti-bacterial spectrum. It has been found that ferulic acid is able to inhibit pathogenic bacteria such as Shigella sonnei, Klebsiella pneumoniae, Enterobacter, Escherichia coli, Citrobacter, Pseudomonas aeruginosa and 11 kinds of microorganisms which causing food corruption. |
Food Industry Applications | In addition to its wide application in medicine, ferulic acid has been approved by some countries to be as a food additive. Japan has approved it to be used in food antioxidants while the United States and some European countries have allowed for adopting some kinds of herbs, coffee, beans with relative high amount of ferulic acid for being antioxidant. Ferulic acid, in the food industry, is mainly used for the preparation of natural vanillin, antioxidants, preservatives, cross-linkers and functional promoting agent. The information is edited by Xiaonan from Chemicalbook. |
Pharmacological effects | Ferulic acid has various effects of inhibiting platelet aggregation, expectorant, and inhibition of Mycobacterium tuberculosis and so on. Clinically ferulic acid is mainly applied to the adjuvant treatment of various kinds of vascular diseases such as atherosclerosis, coronary heart disease, cerebrovascular, renal disease, pulmonary hypertension, diabetic vascular disease, and vasculitis as well as neutropenia and thrombocytopenia. It can be used for treating migraine and vascular headache. As a leukocyte-enhancement drug, this drug also has enhanced hematopoietic function. Therefore, ferulic acid may also be for the treatment of leukopenia and thrombocytopenia. Reference: Xu Jingfeng, Yang Ming (editor) Handbook of clinical prescription drugs. Nanjing: Jiangsu Science and Technology Press .2009 on page 561. |
Synthetic method | Ferulic acid can be obtained through chemical synthesis and extraction. Laboratory dissolves the vanillin, malonic acid and piperidine in pyridine for reaction of three weeks after which with hydrochloric acid precipitation, you can obtain ferulic acid. Figure 2 laboratory synthesis roadmap of ferulic acid |
Uses | It can be used as a food preservative and a kind of organic chemicals. It can be used as the intermediates of cinametic acid. It can also be used as food preservative. It can also be applied to biochemical studies |
Chemical Properties | Pale Yellow Solid |
Uses | antineoplastic, choleretic, food preservative |
Uses | anti-oxidant, anti-inflammatory, sunscreen enhancer |
Uses | Widely distributed in small amounts in plants. Used as an antioxidant and food preservative |
Ferulic Acid Preparation Products And Raw materials |
Raw materials | 2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE |
How is the quality |
The qualities of most products are above 99% purity, same are 99.5% purity. |
2, How is the package |
Foil bag or as customer's required. |
3, How is the storage |
Keep in dry and cool place. |
4, Do I need to pay extra for shipping cost |
No, our price includes the shipping cost already; you need not pay for any tax and others. |
5, Can I order sample to test |
Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier. |
6, minimum quantity |
Usually our minimum quantity is 10g. But you are welcome to order samples to check the quality and our service. |
Company Profile Introduction
Meihua Biological Technology Co.,Ltd, is a global trading company, has been focusing on developing and manufacturing of advanced fine chemical and multiple intermediates. we are all members devoted to working in the filed for seven years. Rich experience gives us great enlightenments in founding of enterprise Meihua Biological Technology Co.,Ltd ,was established on the ground in 2011, is a collection, production, assay and sales into an integrated trading company in one of professional service and exported enterprise. As a mature manufacture, we have rigorous process flow. All final products come to us only by passing HPLC or GC assay. Through 30 procedures in all, we concentrate on every one gram of quality and every one milliliter of purity to your trust. We customize organic material,biochemical reagents,fine chemicals, pharmaceutical intermediates, OLED intermediates, liquid crystal intermediates and glucosides for customers, with high quality, competitive price, professional service and reliable source, and hundreds of species to choose. Such as 4-MPD/5F-ADB/2F-DCK/BK-EBDP/FUB-AMB/ADBF and so on, and new productions including 4433-77-6(BMK)/13605-48-6(PMK)16648-44-5(Benzeneacetic Acid ) etc. Of course, we support various transportation and safe payment. We are aiming at becoming a leading manufacture and trading company in China, even global. We are looking forward to establishing long-term cooperation relationship with customers in the word. We sincerely welcome to contact with us. For more information, please visit our website at http://www.hbmeihua.cn/