1. Product information
Names
Name | Sodium oleate |
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Synonym | More Synonyms |
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Sodium Oleate Biological Activity
Description | Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium[1]. Sodium oleate is a Na+/K+ ATPase activator[2]. |
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Related Catalog | Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Metabolic Disease |
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Target | Na+/K+ ATPase[2] |
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In Vitro | Oleic acid is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Oleic acid prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Oleic acid inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines[1]. |
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References | [1]. Li S, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330. [2]. Jack-Hays MG, et al. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8. |
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Chemical & Physical Properties
Density | 0.9 g/cm3 |
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Boiling Point | 359.999ºC at 760 mmHg |
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Melting Point | 232-235 °C(lit.) |
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Molecular Formula | C18H33NaO2 |
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Molecular Weight | 304.443 |
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Flash Point | 270.099ºC |
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Exact Mass | 304.237823 |
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PSA | 40.13000 |
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LogP | 4.77380 |
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Storage condition | −20°C |
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Stability | Stable. Incompatible with strong oxidizing agents. |
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MSDS
Sodium Oleate MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCHEMICAL NAME : Oleic acid, sodium salt
CAS REGISTRY NUMBER : 143-19-1
MOLECULAR FORMULA : C18-H33-O2.Na
HEALTH HAZARD DATAACUTE TOXICITY DATAROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
REFERENCE : RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,327,1970
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 24,221,1925 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0760 No. of Facilities: 11635 (estimated) No. of Industries: 91 No. of Occupations: 92 No. of Employees: 122970 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0760 No. of Facilities: 8020 (estimated) No. of Industries: 88 No. of Occupations: 92 No. of Employees: 162242 (estimated) No. of Female Employees: 33454 (estimated)
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Safety Information
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Safety Phrases | S22-S24/25 |
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RIDADR | NONH for all modes of transport |
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WGK Germany | 1 |
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RTECS | RK1200000 |
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HS Code | 2916150000 |
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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