1. Product information
| Product Name: | 4-Nitrobenzenesulfonyl chloride |
| Synonyms: | 4-nitro-benzenesulfonylchlorid;4-Nitrophenylsulfonyl chloride;p-Nitrobenzenesulfonic acid chloride;4-Nitrobenzenesulfonyl chloride,95%;4-Nitrobenzenesulfonyl chloride, 95% 25GR;The nitrobenzene sulfonyl chloride;5-Nitrobenzenesulfonyl chloride;4-Nitrobenzenesulfonyl chloride ,99% |
| CAS: | 98-74-8 |
| MF: | C6H4ClNO4S |
| MW: | 221.62 |
| EINECS: | 202-697-9 |
| Product Categories: | Dyestuff Intermediates;Phenyls & Phenyl-Het;Sulphonyl Chlorides;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Benzene derivatives;Benzene series;Phenyls & Phenyl-Het;Sulphonyl Chlorides;98-74-8 |
| Mol File: | 98-74-8.mol |
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| 4-Nitrobenzenesulfonyl chloride Chemical Properties |
| Melting point | 75 °C |
| Boiling point | 143-144 °C (1.5002 mmHg) |
| density | 1.602 (estimate) |
| vapor pressure | 0.009Pa at 20℃ |
| refractive index | 1.6000 (estimate) |
| Fp | 143-144°C/1.5mm |
| storage temp. | Store below +30°C. |
| solubility | soluble in Toluene |
| form | Powder |
| color | yellow |
| PH | 1 (H2O, 20℃) |
| Water Solubility | Insoluble |
| Sensitive | Moisture Sensitive |
| BRN | 746543 |
| Stability: | Moisture Sensitive |
| 4-Nitrobenzenesulfonyl chloride Usage And Synthesis |
| Chemical Properties | yellow to brown powder |
| Uses | 4-Nitrobenzenesulfonyl Chloride is used in the preparation of N-Nosyl-α-amino acid for peptide synthesis. |
| Uses | 4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N,N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines of sulfadiazine, sulfamethoxazole and [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2'-bipyridine, nbs = 4-nitrobenzenesulfonate). |
| Uses | 4-Nitrobenzenesulfonyl chloride was used in the synthesis of
[Cu(bipy)2Cl](nbs) (1) (bipy = 2,2′-bipyridine, nbs = 4-nitrobenzenesulfonate) hydroxylamines of sulfadiazine and sulfamethoxazole solution phase peptide using N-nosyl-α-amino acids.
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
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