4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid

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Min. Order1kg
Purity98.0%min
Cas No641569-94-0
Supply Ability100kg
Update time2023-03-12

LY Global chemicals co.,ltd .

2YR

China

Since2020-09-09

Address103, Building 5, Jinxi Headquarters Port, No. 338 Lianhua Street

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Chemical Properties

Product Name	4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
CAS No	641569-94-0
EC-No	629-968-8
Min. Order	1kg
Purity	98.0%min
Supply Ability	100kg
Release date	2023/03/12

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Basic information

Product Name:	4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
Synonyms:	4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid;Nilotinib EP Impurity D;4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoic acid;Benzoic acid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-;4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidiny]aMino]benzoic acid;2-[(5-Carboxy-2-methylphenyl)amino]-4-(pyridin-3-yl)pyrimidine, 3-{2-[(5-Carboxy-2-methylphenyl)amino]pyrimidin-4-yl}pyridine;Nilotinib Intemediate 2;4-Methyl-3-((4-(pyridin-3-yl)
CAS:	641569-94-0
MF:	C17H14N4O2
MW:	306.32
EINECS:	629-968-8

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Chemical Properties

Melting point	>257oC (dec.)
Boiling point	587.9±60.0 °C(Predicted)
density	1.336
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
pka	4.35±0.10(Predicted)
form	Solid
color	Pale Beige
Stability:	Hygroscopic
CAS DataBase Reference	641569-94-0(CAS DataBase Reference)

Uses

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is used in the preparation of (pyridinyl)-N-[(triazolyl)phenyl]pyrimidinamine derivatives and (pyridinyl)-N-[oxadiazolyl)phenyl]pyrimidinamine derivatives, and can be used in the detection of their activity as antileukemia agents (neoplastic stem cell leukemia). 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is also a Nilotinib (N465300) intermediate, which might be useful in treatment of chronic myelogenous leukemia.

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Company Profile Introduction

LY Global Chemicals Co Ltd.. is a limited liability company specialized in technical research and development, production, development and trade of chemical products. Mainly engaged in the customization and sales of pharmaceutical intermediates, electronic materials, cosmetics raw materials and other fine chemicals. We have many years of export experience, and our customers are all over many countries. Our products are of good quality, competitive price, stable supply, and customers are very satisfied