1. Product information
| Product Name: | 4-Methoxybenzoyl chloride |
| Synonyms: | 4-methoxy-benzoicacichloride;4-methoxy-benzoylchlorid;Benzoyl chloride, 4-methoxy-;Benzoyl chloride, methoxy-;P-ANISOYL CHLORIDE;P-ANISIC ACID CHLORIDE;P-METHOXYBENZOYL CHLORIDE;ANISOYL CHLORIDE |
| CAS: | 100-07-2 |
| MF: | C8H7ClO2 |
| MW: | 170.59 |
| EINECS: | 202-816-4 |
| Mol File: | 100-07-2.mol |
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| 4-Methoxybenzoyl chloride Chemical Properties |
| Melting point | 22 °C(lit.) |
| Boiling point | 262-263 °C(lit.) |
| density | 1.260 g/mL at 20 °C(lit.) |
| vapor pressure | 1.853Pa at 25℃ |
| refractive index | n20/D 1.581(lit.) |
| Fp | 190 °F |
| storage temp. | 2-8°C |
| form | Liquid After Melting |
| color | Clear colorless to brown |
| Odor | Sharp, penetrating. |
| Water Solubility | It reacts in water. |
| Sensitive | Moisture Sensitive |
| Merck | 14,673 |
| BRN | 471918 |
| Stability: | Stable, but reacts violently with water. Ensure no moisture enters the container in which this material is stored, to prevent pressure build-up. Incompatible with water, moisture, strong bases, strong oxidizing agents. |
| 4-Methoxybenzoyl chloride Usage And Synthesis |
| Chemical Properties | 4-methoxybenzoyl chloride appears as an amber-colored crystalline solid. Melting point 72 °F. Corrosive to metals and skin. Vapors may cause serious burns to the eyes. Decompose with water or alcohol, soluble in acetone and benzene. |
| Definition | The hydrolysis of 4-Methoxybenzoyl chloride (OMe) generally occurs through a dissociative mechanism (SN1). The reaction rate is strongly affected by the polarity of the medium and the ability to stabilize the leaving group. Water encapsulated within a reverse micellar system is less polar and less available compared to a continuous aqueous phase; Consequently, the hydrolysis of OMe in the micellar medium is slower than in pure water. |
| Uses | 4-Methoxybenzoyl chloride is used in the synthesis of stilbene and dihydrostilbene derivatives as potential anti-cancer agents. It is also used in the synthesis of coumarin dimers with potential HIV-1 activity. |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.


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