1. Materials information
Names
| Name | 2-methoxy-4-vinylphenol |
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| Synonym | More Synonyms |
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4-Hydroxy-3-methoxystyrene Biological Activity
| Description | 2-Methoxy-4-vinylphenol (2M4VP), a naturally Germination inhibitor, exerts potent anti-inflammatory effects[1][2]. |
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| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology |
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| In Vitro | 2-Methoxy-4-vinylphenol (2M4VP) potently inhibits the translocation of NF-κB p65 into the nucleus by IκB degradation following IκB-α phosphorylation and the phosphorylation of MAPKs such as p38, ERK1/2, and JNK[1]. 2-Methoxy-4-vinylphenol (2M4VP) inhibits hyper-acetylation of histone H3 (Lys9/Lys14) induced by LPS[1]. Western Blot Analysis[1] Cell Line: RAW264.7 cells. Concentration: 0-40 μM. Incubation Time: 24 h. Result: Inhibited the over-expression of iNOS and COX-2 protein in LPS-stimulated RAW264.7 cells. |
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| References | [1]. Jin Boo Jeong, et al. Anti-inflammatory Effect of 2-methoxy-4-vinylphenol via the Suppression of NF-κB and MAPK Activation, and Acetylation of Histone H3. Arch Pharm Res. 2011 Dec;34(12):2109-16. [2]. Hossein Reza Darabi, et al. A Structure-Activity Relationship Study on a Natural Germination Inhibitor, 2-methoxy-4-vinylphenol (MVP), in Wheat Seeds to Evaluate Its Mode of Action. Z Naturforsch C J Biosci. Sep-Oct 2007;62(9-10):694-700. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 245.0±20.0 °C at 760 mmHg |
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| Melting Point | 25-29°C |
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| Molecular Formula | C9H10O2 |
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| Molecular Weight | 150.174 |
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| Flash Point | 111.3±6.7 °C |
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| Exact Mass | 150.068085 |
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| PSA | 29.46000 |
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| LogP | 1.93 |
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| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
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| Index of Refraction | 1.578 |
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| Storage condition | 2-8°C |
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MSDS
4-Hydroxy-3-methoxystyrene MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCAS REGISTRY NUMBER : 7786-61-0
MOLECULAR FORMULA : C9-H10-O2
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATATEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 500 umol/L
REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988
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Safety Information
| Symbol | 
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | SL8205000 |
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| HS Code | 2909500000 |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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