Name | 4'-Hydroxy-2,4-dimethoxychalcone |
Description | 4'-Hydroxy-2,4-dimethoxychalcone, a naturally occurring chalcone derivative from the herbal resin of the red geranium [Dragon's Blood], exhibits a wide range of biological activities including anti-malarial, anti-bacterial, anti-fungal, and anti-protozoa properties. |
In vitro | 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) exhibits activity against P. falciparum strains D6 and W2, with IC50 values of 4.2 μM and 4.8 μM, respectively. [1] |
In vivo | 'Oral administration of 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) at 160 mg/kg in ICR mice resulted in a T1/2 of 1.94 hours, Cmax of 158 ng/mL, and AUC of 384 ng•h/mL.[1]' |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
Keywords | P. falciparum | Fungal | Bacterial | 4'-Hydroxy-2,4-dimethoxychalcone | 4'Hydroxy2,4dimethoxychalcone | 4' Hydroxy 2,4 dimethoxychalcone |
Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Doxycycline (hyclate) | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hydroxychloroquine | Doxycycline | Geraniol | Dimethyl sulfoxide | Ethyl acetoacetate |
Related Compound Libraries | Anti-Parasitic Compound Library | Flavonoid Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Fungal Compound Library | Anti-Bacterial Compound Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |