| CAS: | 106-38-7 |
| MF: | C7H7Br |
| MW: | 171.03 |
| EINECS: | 203-391-8 |
| Product Categories: | alkyl bromide;Building Blocks;Intermediates;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;Aromatic Hydrocarbons (substituted) & Derivatives;Organics;Miscellaneous;4-Alkylbromobenzenes (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;Aryl;C7;Halogenated Hydrocarbons;K00001 |
| Mol File: | 106-38-7.mol |
 |
|
| 4-Bromotoluene Chemical Properties |
| Melting point | 26-29 °C(lit.) |
| Boiling point | 184 °C(lit.) |
| density | 1.39 g/mL at 25 °C(lit.) |
| refractive index | 1.549 |
| Fp | 185 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.11g/l insoluble |
| form | Crystalline Low Melting Mass |
| color | White |
| Specific Gravity | 1.390 |
| Water Solubility | <0.1 g/100 mL at 24 ºC |
| Merck | 14,1439 |
| BRN | 1903636 |
| CAS DataBase Reference | 106-38-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-bromo-4-methyl-(106-38-7) |
| EPA Substance Registry System | p-Bromotoluene (106-38-7) |
| 4-Bromotoluene Usage And Synthesis |
| Description | 4-Bromotoluene is a p-substituted aryl bromide. As a toluene derivative, it is used as a solvent and starting material for organic synthesis and is found in paints, paint thinners, glues, and other products. 4-Bromotoluene was used in the synthesis of ketones by Cu/Pd-catalyzed decarboxylative cross-coupling reaction. It is also used in manufacturing pharmaceuticals (especially for antihypertensive like losartan, Irbesartan), pesticides and other organic compounds1-3. |
| References | https://www.sigmaaldrich.com/catalog/search?term=4-Bromotoluene&interface=All&N=0&mode=match%20partialmax&lang=en®ion=US&focus=product https://bbzfrankie.wordpress.com/2013/11/21/application-of-4-bromotoluene/ https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+6015
|
| Chemical Properties | white crystalline low melting mass, soluble in ethanol, ether and benzene, insoluble in water. toxic, harmful if swallowed, irritating to eyes, respiratory system and skin. 4-bromotoluene is a raw material of organic synthesis, which can be used as the manufacture of p-bromobenzyl, p-bromodibromobenzyl and p-bromobenzaldehyde, etc. |
| Uses | 4-Bromotoluene was used in the synthesis of ketones by Cu/Pd-catalyzed decarboxylative cross-coupling reaction. 4-Bromotoluene undergoes Heck reaction with styrene in the presence of in situ generated palladium complexes of phosphine-functionalized N-heterocyclic carbene ligands. |
| Preparation | 4-Bromotoluene is prepared by diazotization and replacement of p-toluidine. First, add aqueous sulfuric acid solution to crushed p-toluidine while hot, cool to 5°C, and slowly add aqueous sodium nitrite solution until the starch potassium iodide test paper turns blue. Then add a small amount of urea to destroy the excess of sodium nitrite. Then add the synthesized cuprous bromide to hydrobromic acid, heat it to boiling, then slowly add the above diazo salt and distill it until no oil-like substance comes out. Wash, dry, filter, distill at atmospheric pressure and collect 183-185℃ fraction to obtain 4-Bromotoluene. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Advantage
In stock
Japan
