4-Aminoacetophenone

• DATA ITEMS CITED :

• 7

• MOLECULAR FORMULA :

• C8-H9-N-O

• MOLECULAR WEIGHT :

• 135.18

• WISWESSER LINE NOTATION :

• ZR DV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Oral

• SPECIES OBSERVED :

• Rodent - rat

• DOSE/DURATION :

• 381 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 14,465,1983

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Intraperitoneal

• SPECIES OBSERVED :

• Rodent - rat

• DOSE/DURATION :

• 260 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 80,31,1944

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Oral

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 596 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 14,465,1983

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Intraperitoneal

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 300 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

• TYPE OF TEST :

• LD - Lethal dose

• ROUTE OF EXPOSURE :

• Oral

• SPECIES OBSERVED :

• Mammal - dog

• DOSE/DURATION :

• >70 mg/kg

• TOXIC EFFECTS :

• Blood - methemoglobinemia-carboxyhemoglobin

• REFERENCE :

• JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 80,31,1944

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Oral

• SPECIES OBSERVED :

• Bird - wild bird species

• DOSE/DURATION :

• 133 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983