| CAS: | 586-89-0 |
| MF: | C9H8O3 |
| MW: | 164.16 |
| EINECS: | 209-588-5 |
| Product Categories: | intermediate;Benzoic Acids (Building Blocks for Liquid Crystals);Aromatic Acetophenones & Derivatives (substituted);Bifunctional Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;Drug Intermediates;Benzoic acid |
| Mol File: | 586-89-0.mol |
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| 4-Acetylbenzoic acid Chemical Properties |
| Melting point | 208-210 °C(lit.) |
| Boiling point | 251.61°C (rough estimate) |
| density | 1.2132 (rough estimate) |
| refractive index | 1.5380 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystals or Crystalline Powder |
| pka | pK1: 3.70 (25°C) |
| color | White |
| Water Solubility | soluble |
| BRN | 2207355 |
| InChIKey | QBHDSQZASIBAAI-UHFFFAOYSA-N |
| CAS DataBase Reference | 586-89-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Acetylbenzoic acid(586-89-0) |
| 4-Acetylbenzoic acid Usage And Synthesis |
| Uses | 4-Acetylbenzoic Acid is an intermediate used to prepare Curcumin Analogs with anti-oxidant activities. It is also used in the synthesis of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors. |
| Chemical Properties | White to light yellow crystal powder |
| Uses | 4-Acetylbenzoic acid was used in the preparation of an ester-derivative of paclitaxel. |
| Synthesis Reference(s) | Synthesis, p. 715, 1974 DOI: 10.1055/s-1974-23412 |
| Purification Methods | 4-AcDissolve the acid in 5% aqueous NaOH, extract it with Et2O, and acidify the aqueous solution. Collect the precipitate, and recrystallise it from boiling H2O (100 parts) using decolorising charcoal [Pearson et al. J Org Chem 24 504 1959, Pearson et al. J Chem Soc 265 1957, Detweiler & Amstutz J Am Chem Soc 72 2882 1950, Bordwell & Cooper J Am Chem Soc 74 1058 1952]. [Beilstein 10 IV 2769.] |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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