Finerenone Intermediate (CAS 1050477-27-4)
Google Keywords: Finerenone Intermediate, CAS 1050477-27-4, CKD Drug Synthesis, Mineralocorticoid Receptor Antagonist Intermediates, GMP API Manufacturing
🌟 Product Overview
Finerenone Intermediate (CAS 1050477-27-4) is a high-purity chemical intermediate pivotal in synthesizing Finerenone, a non-steroidal mineralocorticoid receptor antagonist (MRA) approved for treating chronic kidney disease (CKD) and heart failure in patients with type 2 diabetes. This intermediate ensures precision and compliance in API production, supporting scalable and cost-effective pharmaceutical manufacturing.
Primary Function: Critical building block for Finerenone API synthesis, enabling robust chemical transformations.
Applications: CKD/heart failure drug development, metabolic disorder therapies, and large-scale API production.
✅ Key Advantages
🔹 Ultra-High Purity | ≥99.0% (HPLC/GC verified) | Meets ICH Q11 guidelines for pharmaceutical intermediates.
🔹 Scalable Process | Optimized for high-yield, low-impurity synthesis in industrial-scale manufacturing.
🔹 Regulatory Ready | Fully characterized (NMR, HRMS) to support FDA/EMA filings and GMP compliance.
🧪 Applications
API Manufacturing: Enables efficient synthesis of Finerenone with consistent quality and yield.
Process Development: Accelerates R&D for optimizing synthetic routes and reducing production costs.
Quality Control: Used in analytical method validation and batch release testing.
📜 Quality Assurance
Testing Methods: HPLC, GC, NMR, HRMS, and FTIR for structural confirmation and purity analysis.
Standards: Complies with USP <1086>, EP 10.0, and ISO 9001:2015 certified production protocols.
📈 Market Trends
The global CKD treatment market is projected to reach $19.3 billion by 2030 (CAGR 6.7%), driven by rising diabetes-related kidney diseases and demand for targeted therapies like Finerenone. This intermediate plays a vital role in meeting the growing need for innovative cardiorenal drugs.
Empower your CKD drug production with Finerenone Intermediate – precision, scalability, and compliance for cutting-edge API synthesis.
China
