4-(2,4-Difluorobenzoyl)piperidine Hydrochloride NEW

4-(2,4-Difluorobenzoyl)piperidine Hydrochloride (CAS: 106266-04-0)

Physical and Chemical Properties

Chemical Information

• IUPAC Name: 4-(2,4-Difluorobenzoyl)piperidine hydrochloride

• Synonyms: 1-(2,4-Difluorobenzoyl)piperidine hydrochloride

• Molecular Formula: C12H14ClF2NO

• Molecular Weight: 261.7 g/mol

Structure and Properties

• Chemical Structure: The compound consists of a piperidine ring substituted at the 4-position with a 2,4-difluorobenzoyl group.

• Appearance: Typically a white to off-white crystalline powder or solid.

• Solubility: Soluble in water and organic solvents like methanol and ethanol.

• Melting Point: Data may vary but generally falls within a typical range for similar piperidine derivatives.

Applications and Uses

• Pharmaceuticals: Used as an intermediate in the synthesis of pharmaceutical compounds, particularly those involving substituted piperidines.

• Chemical Research: Utilized in research to study the properties and reactions of difluorobenzoyl-substituted piperidines, which have potential applications in medicinal chemistry.

• Organic Synthesis: Employed as a building block in the synthesis of more complex organic molecules.

Safety and Handling

• Personal Protective Equipment (PPE): Use appropriate gloves, protective eyewear, and lab coats to prevent contact with skin and eyes. Handle under a fume hood to avoid inhalation.

• Storage: Store in a cool, dry place, away from incompatible substances such as strong oxidizing agents.

• Hazards:

• Corrosive: Can cause severe skin burns and eye damage.

• Inhalation: Harmful if inhaled, causing respiratory tract irritation.

• Handling: Handle with care, avoiding any form of contact and inhalation.

• First Aid Measures:

• Inhalation: Move to fresh air. If breathing is difficult, seek medical attention.

• Skin Contact: Wash off with soap and plenty of water. Remove contaminated clothing and seek medical attention.

• Eye Contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

• Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical attention immediately.

References and Resources

4-(2,4-Difluorobenzoyl)piperidine hydrochloride is valuable in various industrial and research applications due to its unique chemical structure and reactivity. For precise safety guidelines and detailed information, always refer to the specific Material Safety Data Sheet (MSDS) provided by the manufacturer or supplier.