Dexamethasone acetate
MF:C24H31FO6.H2O
CAS:55812-90-3
Appearance:white powder
Purity:99%
Dexamethasone has many uses in the treatment of cancer. It is classified as a glucocorticosteroid
What This Drug Is Used For:
As an anti-inflammatory medication. Dexamethasone relieves inflammation in various parts of the body. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain, and to treat eye inflammation.
To treat or prevent allergic reactions.
As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.
As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma.
To treat nausea and vomiting associated with some chemotherapy drugs.
Used to stimulate appetite in cancer patients with severe appetite problems.
Also used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).
The COA of Dexamethasone acetate:
| Product Name |
MFG. Date |
Lot No. |
Outer Packing |
Report Date |
| Dexamethasone Acetate |
2017-04-09 |
2017040903 |
1kg/bag |
2017-04-12 |
| Test Items |
Specification |
Test Results
|
| Ph.Eur.5 |
USP30 |
Ph.Eur.5 |
USP30 |
| Characters |
A white or almos white, crystalline powder |
White crystalline powder |
| Identification |
A. IR Absorption |
A. IR Absorption |
complies |
complies |
| B. TLC |
B. UV Absorption |
complies |
complies |
| Specific optical rotation |
Between +84°and +90° |
Between +82°and +88° |
+86.5° |
| Related substances |
Any individual impurity not more than 0.5% |
Any individual impurity not more than 1.0% |
0.37% |
0.34% |
| Total impurities not more 1.0% |
Total impurities not more 2.0% |
0.54% |
0.59% |
| Loss on drying |
Not more than 0.5% |
Not more than 0.4% |
0.11% |
| Residue on ignition |
Not more than 0.1% |
0.02% |
| Residual solvents |
Acetone |
≤5000ppm |
5ppm |
Ethyl acetate |
≤5000ppm |
58ppm |
Pyridine |
≤200ppm |
Not detect out |
| Assay |
Between 97.0% and 103.0% |
Between 97.0% and 102.0% |
100.0% |
100.1% |
| Heavy metals |
Not more than 0.002% |
complies |
Micronization |
90% not more than 15 microns |
90% not more than 15 microns |
China
