Betamethasone 17,21-dipropionate Quick details
English Synonyms: BETAMETHASONE DIPROPIONATE;BETAMETHASONE 17,21-DI-PROPIONATE;BETAMETHASONE 17-ALPHA,21-DIPROPIONATE;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE;9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17,21-DIPROPIONATE;9a-fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate;diproderm;diprolene
CAS NO.: 5593-20-4
Assay: 99%
Molecular Formula:C28H37FO7
Molecular Weight:504.59
Quality Standard: BP2004 EP5 USP28.
Appearance: White or yellowish crystalline powder
Usage: Topical anti-inflammatory adrenal hormone class medicine
Betamethasone 17,21-dipropionate Prolonging products: cream, ointment, betamethasone dipropionate betamethasone cream
Betamethasone 17,21-dipropionate Use: for atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis and pruritus.
Betamethasone 17,21-dipropionate Dosage: External: 2-4 times a day, applied to the affected area, and gently rub a moment. Long-term use can cause local skin atrophy, telangiectasia, pigmentation, folliculitis, perioral dermatitis, and secondary infections. Banned for infectious skin diseases, such as impetigo, body ringworm, jock itch. 2. disabled allergy to this product.
Betamethasone 17,21-dipropionate COA
Product name |
Betamethasone dipropionate |
CAS
CAS No. |
5593-20-4 |
Outer Packing |
1KG
1KG/bag |
Production date |
2015.08.02 |
Shelf life |
2018.08.01 |
Standard adopted |
USP34
USP34 |
Items of analysis |
Specification |
Results |
Description |
White or almost white crystalline powder |
almost white crystalline powder |
Solubility |
practically insoluble in water,freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol |
complies |
Identification (IR,HPLC,TLC) |
complies with the Standard |
complies |
Specific rotation (In dioxan) |
+63°~+70° |
+65° |
Loss on drying |
max. 1.0% |
0.11% |
Residue on ignition |
max. 0.2% |
0.002% |
Single impurity |
max. 1.0% |
0.16% |
Sum impurities |
max. 2.0% |
0.47% |
Assay |
97.0%~103.0% |
99.5% |
Acetone |
≤ 5000ppm |
Complies |
Methanol |
≤ 3000ppm |
Complies |
Chloroform |
≤ 60ppm |
Complies |
1,4-dioxane |
≤ 380ppm |
Complies |
Pyridine |
≤ 200ppm |
Complies |
Conclusion |
Qualified |