Basic information:
Product Name |
Betamethasone |
Synonyms |
(11beta,16beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20;16-beta-Methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione;17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-9-alpha-fluoro-11-bet;6beta)-;9-alpha-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1, |
CAS |
378-44-9 |
MF |
C22H29FO5 |
MW |
392.46 |
EINECS |
206-825-4 |
Product Categories |
Mol File: 378-44-9.mol |
MP |
235-237°C |
refractive index |
118 ° (C=1, Dioxane) |
storage |
temp. 0-6°C |
Merck |
1180 |
Description:
Betamethasone, dexamethasone of isomers, the role and purpose with dexamethasone acetate, the sodium and water retention effect and dose than the latter is small. Glucose metabolism and anti-inflammatory effect than hydrocortisone strong as hydrocortisone 15 times, but the effect of sodium retention hydrocortisone hundred times more, in primary adrenal hypofunction in with glucocorticoid steroid replacement therapy used together.
Also suitable for low renin and low aldosterone syndrome, autonomic neuropathy induced orthostatic hypotension. Because of the goods taken orally is prone to cause edema, more topically applying topical treatment for seborrheic eczema, contact dermatitis, anal, genital itching embolism. Mainly used for allergic and autoimmune inflammatory diseases. It is used for activities rheumatism, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, but also for the comprehensive treatment of certain infections.