1. Materials information
Use of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
| Name | 7-hydroxy-3,4-dihydro-1H-quinolin-2-one |
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| Synonym | More Synonyms |
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3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Biological Activity
| Description | 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1]. |
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| Related Catalog | Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease |
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| Target | IC50: 183 μM (MAO-A)[1] |
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| In Vitro | 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1]. |
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| References | [1]. Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 403.7±45.0 °C at 760 mmHg |
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| Melting Point | 233-237 °C |
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| Molecular Formula | C9H9NO2 |
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| Molecular Weight | 163.173 |
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| Flash Point | 198.0±28.7 °C |
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| Exact Mass | 163.063324 |
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| PSA | 49.33000 |
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| LogP | 0.99 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.604 |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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