| CAS: | 948-65-2 |
| MF: | C14H11N |
| MW: | 193.24 |
| EINECS: | 213-436-3 |
| Product Categories: | Pyridines;Building Blocks;Heterocyclic Building Blocks;Building Blocks;Heterocycle-Indole series;intermediates;Indole;Heterocyclic Compounds;Indoles;Simple Indoles;C13 to C27;Chemical Synthesis;Heterocyclic Building Blocks |
| Mol File: | 948-65-2.mol |
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| 2-Phenylindole Chemical Properties |
| Melting point | 188-190 °C (lit.) |
| Boiling point | 250 °C/10 mmHg (lit.) |
| density | 1.1061 (rough estimate) |
| refractive index | 1.5850 (estimate) |
| Fp | 250°C/10mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | almost transparency in Methanol |
| pka | 16.80±0.30(Predicted) |
| form | Powder |
| color | Off-white to beige or slightly green |
| CAS DataBase Reference | 948-65-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-Indole, 2-phenyl-(948-65-2) |
| EPA Substance Registry System | 1H-Indole, 2-phenyl- (948-65-2) |
| 2-Phenylindole Usage And Synthesis |
| Chemical Properties | off-white to beige or slightly green powder |
| Uses | Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions† |
| Uses | Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole). |
| Uses | Reactant for preparation of:
Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators Organic light emitting diodes (OLEDs) Anti inflammatory agents Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors Agents for cancer and malaria therapy Antifungal and antibacterial agents Fluorescent probes
Reactant in:
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| Preparation | 2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air. |
| Definition | ChEBI: 2-phenyl-1H-indole is a phenylindole. |
| Synthesis Reference(s) | Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509 |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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