Product Name: 2'-Fluoro-2'-deoxyuridine
Synonyms: 1-(2'-FLUORO-2'-DESOXY-BETA-D-RIBOFURANOSYL)URACIL;2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-BETA-D-RIBOFURANOSYL);2'-FLUORO-2'-DEOXYURIDINE;2'-FLUORO-2'-DESOXY-URIDINE;2'-DEOXY-2'-FLUOROURIDINE;2'-FLUORO-D-URIDINE;2'-FUDR;2'-FU
CAS: 784-71-4
MF: C9H11FN2O5
MW: 246.19
EINECS: 1806241-263-5
Product Categories: Bases & Related Reagents;Intermediates & Fine Chemicals;API intermediates;Biochemistry;Nucleotides;Pharmaceuticals;Pyridines, Pyrimidines, Purines and Pteredines;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;784-71-4;Nucleosides;Modified(deoxy)nucleoside;Nucleosides-2'-F Nucleosides;1
2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity.