2-Chloro-5-methylpyrimidine CAS 22536-61-4 | Customized Supplier of Highly Reactive Heterocyclic Intermediates
[Core Keywords]: 2-Chloro-5-methylpyrimidine Supplier, CAS 22536-61-4, Pyrimidine Pharmaceutical Intermediates, Agrochemical Raw Materials
Product Basic Information
Chemical Name: 2-Chloro-5-methylpyrimidine
CAS Number: 22536-61-4 (Enhanced Title-Level Keyword)
Molecular Formula: C5H5ClN2
Appearance: Colorless to pale yellow crystalline solid
Purity: ≥99.0% (GC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimization)
| Property | Parameter Value |
|---|
| Molecular Weight | 128.56 g/mol |
| Melting Point | 34-37°C (Dynamic DSC) |
| Boiling Point (10 mmHg) | 85-88°C |
| Density (25°C) | 1.25 g/cm³ |
| Solubility | Soluble in THF, dichloromethane; slightly soluble in water (<0.5%) |
| Storage Conditions | Store in a light-protected, sealed container at -20°C for long-term preservation |
Upstream and Downstream Industry Chain Integration
▶ Upstream Raw Materials and Core Intermediates: 5-Methylpyrimidine-2-ol, Thionyl Chloride (SOCl₂)
▶ Downstream Applications and Expansions
Antiviral Drugs: Key Fragment of HCV Protease Inhibitors
Agricultural Fungicides: Precursor of Methoxyacrylate Fungicides
Functional Materials: Modified Monomer for Liquid Crystal Materials
CRO/CDMO: Kinase Inhibitor Molecular Library Construction
Industry Solutions and Technical Advantages
| Application Area | Typical Scenario | Technical Advantages |
|---|
| Nucleoside Analog Synthesis | Preparation of Tenofovir Derivatives for Anti-HIV Drugs | Chlorination Reaction Yield >95% (HPLC) |
| Agrochemical Formulation Development | Modification of Novel Broad-Spectrum Fungicide Molecular Skeletons | Thermal Stability (Decomposition Rate <2% at 150°C/24h) |
| Optoelectronic Materials | Electron Transport Layer in Organic Light-Emitting Diodes (OLED) | Purity ≥99.9% (Sublimation Purification Process) |
| Molecular Probes | Protein Labeling Click Chemistry Reaction Substrates | Active Site Selectivity >98% |
SEO Keyword Matrix
Core Keyword Layout: "2-Chloro-5-methylpyrimidine Price", "CAS 22536-61-4 Technical Parameters", "High-Purity Pyrimidine Derivative Supplier"
Long-Tail Keyword Combinations: "Custom Synthesis of Antiviral Drug Intermediates", "Manufacturer of Pyrimidine-Based Raw Materials for Agricultural Fungicides", "GMP-Grade 22536-61-4 Supplier"
Quality System and Service Guarantee
✅ cGMP Compliant Production: Complies with ICH Q11 Specifications for Active Pharmaceutical Ingredient Starting Materials
✅ Customized Services: Supports orders from gram-scale to ton-scale (MOQ 100g)
✅ Analysis Report: Provides a full set of structural confirmation documents including HPLC/GC-MS/NMR
✅ Global Logistics: UN-standard packaging (4°C cold chain transportation optional)
China
