2-Amino-4,6-dichloropyrimidine CAS 56-05-3 | Core Raw Material Supplier for Multifunctional Pyrimidine Intermediates
[Core Keywords]: 2-Amino-4,6-dichloropyrimidine Supplier, CAS 56-05-3, Pyrimidine Pharmaceutical Intermediates, Agrochemical Synthesis Building Blocks
Product Basic Information
Chemical Name: 2-Amino-4,6-dichloropyrimidine
CAS Number: 56-05-3 (Title-Level Keyword Enhancement)
Molecular Formula: C4H3Cl2N3
Appearance: White to off-white crystalline powder
Purity: ≥99.0% (HPLC, Pharmaceutical Grade Standard)
Key Physical and Chemical Properties (Structured Data Optimization)
| Property | Parameter Value |
|---|
| Molecular Weight | 164.00 g/mol |
| Melting Point | 178-182°C (DSC Measurement) |
| Boiling Point (Reduced Pressure) | 285-290°C (Decomposition) |
| Density (25°C) | 1.58 g/cm³ |
| Solubility | Soluble in DMSO, DMF; slightly soluble in ethanol; insoluble in water |
| Storage Conditions | Store in a cool, dry place, sealed at room temperature, and away from light |
Upstream and Downstream Industry Chain Integration
▶ Upstream Raw Materials and Key Intermediates: Barbituric acid, Thionyl chloride (SOCl₂)
Process Optimization: Low-temperature chlorination technology (Selectivity >98%, By-products <0.5%)
▶ Downstream Applications Expansion
Anticancer Drugs: Key precursor for thymidylate synthase inhibitors
Agricultural Herbicides: Molecular skeleton modification for sulfonylurea herbicides
Functional Materials: Ligand synthesis for metal-organic frameworks (MOFs)
Fluorescent Dyes: Biomarker probes, heterocyclic structural units
Industry Solutions and Technical Advantages
| Application Area | Typical Scenario | Technical Advantages |
|---|
| Anticancer Drug Development | Synthesis of 5-fluorouracil derivatives | Amino-directed substitution yield >97% (LC-MS verified) |
| Agrochemical Formulations | Intermediates for novel sulfonylurea herbicides | Chlorine atom reactivity optimization (stable at pH 4-9) |
| Optoelectronic Materials | Modification of OLED electron transport layer materials | Purity ≥99.9% (gradient sublimation process) |
| Molecular Diagnostics | Synthesis of linkers for CRISPR gene editing reagents | Amino protection/deprotection efficiency >95% |
SEO Keyword Matrix
Core Words Layout: "2-Amino-4,6-dichloropyrimidine Price", "CAS 56-05-3 Technical Parameters", "High-Purity Pyrimidine Derivatives Supplier"
Long-Tail Keyword Combinations: "Custom Synthesis of Anticancer Drug Intermediates", "Raw Material Producer for Sulfonylurea Herbicides", "Pharmaceutical Grade 56-05-3 Manufacturer"
Quality System and Service Commitment
✅ cGMP Compliant Production: Complies with ICH Q7 standards for Active Pharmaceutical Ingredient (API) starting materials
✅ Customized Services: Supports orders from grams to hundreds of kilograms (MOQ 50g)
✅ Analysis Report: Provides a full set of documents including HPLC, 1H NMR, and elemental analysis
✅ Global Logistics: UN-certified packaging (optional room temperature/cold chain transportation)
China
