1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures.
| Name | 2-(2-Bromoethyl)-1,3-dioxolane | EINECS | 242-551-1 |
| CAS No. | 18742-02-4 | Density | 1.489 g/cm3 |
| PSA | 18.46000 | LogP | 1.14430 |
| Solubility | immiscible in water | Melting Point | N/A
|
| Formula | C5H9BrO2 | Boiling Point | 200.9 °C at 760 mmHg |
| Molecular Weight | 181.029 | Flash Point | 85 °C |
| Transport Information | UN 2810 6.1/PG 3 | Appearance | Clear colorless to yellow or brown liquid |
Appearance and properties: Transparent yellow to brown liquid
Density: 1.542 g/mL at 25 °C(lit.)
Boiling point: 68-70 °C8 mm Hg(lit.)
Flash point: 149 °F
Refractive index: n20/D 1.479(lit.)
Water solubility: immiscible
Stability: Stable under normal temperatures and pressures.
Storage condition: 2-8ºC
Vapor pressure: 0.162mmHg at 25°C


