China| Product Name | Tetracaine |
| CAS No | 94-24-6 |
| EC-No | 202-316-6 |
| Min. Order | 10g |
| Purity | 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customized packaging |
| Supply Ability | 100kg |
| Release date | 2022/12/29 |
Tetracaine CAS 202-316-6 Safe and Fast Delivery
| Tetracaine Usage And Synthesis |
| Uses | Tetracaine is used in assessing the potential for drug-nanoparticle surface interactions to improve drug penetration into the skin. |
| Description | Tetracaine is a local anesthetic or numbing medicine that is used to numb the throat, eyes, or nose. Normally, the drug is administered before starting a surgery to decrease pain from the procedure. Tetracaine is applied to the eyes 30 minutes before the start of an intravenous and its effects can last up to 15 minutes. |
| Mechanism of Action | Tetracaine acts by blocking the nerve systems. It does this by blocking the sodium ion channels needed for the conduction and initiation of neural impulses, thereby affecting the local anesthesia. Tetracaine acts by altering the function of calcium release channels that controls the release of calcium frim intracellular cells. |
| Precautions | No studies have revealed whether the medicine can affect an unborn child; however, it is important to inform the doctor if pregnant while using it. Informing the doctor is paramount if breastfeeding a baby, as no known research has illustrated whether tetracaine can pass into breast milk or harm a nursing baby. To make tetracaine safe, it is important to inform the doctor if one has a history of spinal or brain injury, heart diseases, eye problems, a blood vessel disorder, open sores, skin injury in the area where the medicine will be applied. Tetracaine should never be orally taken since it is typically designed for use on the skin only. If the medicine gets in the mouth, nose, vagina, or rectum, rinse with water. |
| Application | Tetracaine topical (for the skin) is used to numb various body parts before a surgical procedure or a medical test. Conversely, tetracaine ophthalmic drops are used as local anesthetic for the eyes. |
| Dosage | Always follow all direction on the prescription label. Do not use the medicine in smaller or larger amounts or for longer than recommended. |
| Side Effects | Seek emergency medical advice in case of any of the following allergic reactions: difficult breathing, hives, swelling of the throat, tongue, lips, or face. Stop using the drug and call the physician if one has severe burning, swelling, stinging, or other irritation of the treated skin. Other alarming symptoms include eye watering, irritation, and increased sensitivity to light. Common side effects include burning, stinging, or itching at the point of application of the medicine; numbness in places where tetracaine has been accidentally applied or skin redness or tenderness. Nonclinical Toxicology Studies conducted to reveal the genotoxicity of tetracaine have not indicated its mutagenesis, carcinogenicity, or impairment of fertility. |
| Chemical Properties | White or light-yellow, waxy solid. Very slightly soluble in water; soluble in alcohol, ether, benzene, chloroform. |
| Uses | analgesic |
| Definition | ChEBI: A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia. |
| Biological Functions | Tetracaine hydrochloride (Pontocaine) is an ester of PABA that is an effective topical local anesthetic agent and also is quite commonly used for spinal (subarachnoid) anesthesia. Epinephrine is frequently added to prolong the anesthesia.Tetracaine is considerably more potent and more toxic than procaine and cocaine. It has approximately a 5-minute onset and 2 to 3 hours of action. |
| General Description | Tetracaine was developed to address the low potency andshort duration of action of procaine and chloroprocaine. The addition of the butyl side chain on the para nitrogen increasesthe lipid solubility of the drug and enhances the topical potencyof tetracaine. The plasma half-life is 120 to 150 seconds.Topically applied tetracaine to unbroken skin requires 30 to 45minutes to confer topical anesthesia. Tetracaine 4% gel is superiorthan eutectic mixture with lidocaine (EMLA) (an emulsionof lidocaine and prilocaine) in preventing pain associatedwith needle procedures in children. Tetracaine metabolism issimilar to procaine ester metabolism yielding parabutylaminobenzoicacid and dimethylaminoethanol and conjugatesexcreted in the urine. The pKa of the dimethylated nitrogen is8.4 and tetracaine is formulated as a hydrochloride salt with apH of 3.5 to 6.0. The increased absorption from topical siteshas resulted in reported toxicity. Overdoses of tetracaine mayproduce central nervous system (CNS) toxicity and seizure activitywith fatalities from circulatory depression reported.No selective cardiac toxicity is seen with tetracaine althoughhypotension has been reported. Tetracaine is employed for infiltrationanesthesia, spinal anesthesia, or topical use. |
| Veterinary Drugs and Treatments | Tetracaine is more irritating than proparacaine but is sometimes used in veterinary medicine. It is indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure (tonometry), removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy. Tetracaine is also indicated to produce local anesthesia prior to surgical procedures in humans such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics. Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solution enters the eye through the incision. |
Our Service
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.We can provide the reasonable price, high quality products and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions, we’ll treat every email and message within 24 hours usually much faster.
5.We can provide you a discount if you place a substantial order with us.
6.Products can be packaged and company logo can be customized according to customer requirements.
Our company
Guangzhou Biocar Biotechnology Co.,Ltd.,formerly known as Guangdong Yangye Pharmaceutical Factory established in 2005, which is affiliated to Wuhan Biocar Group. With the rise of Internet +, company's business process is accelerating. The company's board of directors has decided to establish Guangzhou Yangye Biotechnology Co., Ltd. at the end of 2016.
Guangzhou Biocar Biotechnology Co.,Ltd. is located near Zhujiang New Town, Tianhe District, one of the prosperous areas in Guangzhou. This helps facilitate business negotiations at home and abroad. It is a high-tech enterprise centered in Guangdong, radiating across our country and facing the world. And it is mainly engaged in the research, development and sales of new chemical raw materials, the custom synthesis and import and export of pharmaceutical intermediates and APIs, the agency sales of pharmaceutical chemicals, the research and development, production and sales of flavors, fragrances and chemical raw materials. Its factory covers an area of more than 4,000 acres and has more than 600 employees.
Guangzhou Biocar Biotechnology has a production base for deep processing of feed additives and veterinary drug intermediates based on main pharmaceutical intermediates.
It has always adhered to the tenet of "Being faithful, cultivating harmony and achieving win-win cooperation" and treats every customer sincerely.
We are looking forward to cooperating with you sincerely, and making mutual benefit and brilliance!
Delivery
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitateyou track the express
Transaction requirements: serious and sincere, pragmatic and efficient
1. We support the verification of the authenticity of our warehouse andproducts through video conversations.
2. If we release this product, it means that we can also produce its similarproducts.
3. We have insured each product, if the goods are lost or damaged, wecan provide a 100% refund.
4. Delivery time limit: 4-7 days in the UK, 10-15 days in other countries.
5. Company qualification: Seven years since its establishment, with 2factories and 8 laboratories,has cooperated with Wuhan Textile Universityand set up a talent reserve base, which can accept the customization ofpharmaceutical intermediates and the mass production of large chemicals.
6. Quality inspection certificate: every product has its third-party qualityinspection certificate to ensure the safety of the product.
7. Advantages: can be customized production, can be shipped in batches,price concessions, high timeliness.
8.Can assist customers in brand design and printing, and has successfullybuilt OMEGA, ZE and other brands
9. Payment method: Western Union, MoneyGram, Bitcoin, bank transfer, remitlyare currently accepted.
10.Reject malicious inquiries, reject scammers
11.Provide door-to-door transportation, as well as normal customs clearanceservices
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Company Profile Introduction
Guangzhou Biocar Biotechnology Co., Ltd., formerly known as Guangdong Yangye Pharmaceutical Factory established in 2005, which is affiliated to Wuhan Biocar Group. With the rise of Internet +, company′s business process is accelerating. The company′s board of directors has decided to establish Guangzhou Yangye Biotechnology Co., Ltd. At the end of 2016. Guangzhou Biocar Biotechnology Co., Ltd. is located near Zhujiang New Town, Tianhe District, one of the prosperous areas in Guangzhou city. This helps facilitate business negotiations at home and abroad. It is a high-tech enterprise centered in Guangdong Province, radiating across our country and facing the world. And it is mainly engaged in the research, development and sales of new chemical raw materials, the custom synthesis and import and export of pharmaceutical intermediates and APIs, the agency sales of pharmaceutical chemicals, the research and development, production and sales of flavors, fragrances and chemical raw materials. Its factory covers an area of more than 4, 000 acres and has more than 600 employees. Guangzhou Biocar Biotechnology has a production base for deep processing of feed additives and veterinary drug intermediates based on main pharmaceutical intermediates. It has always adhered to the tenet of "Being faithful, cultivating harmony and achieving win-win cooperation" and treats every customer sincerely.
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