INCI Name: HEXYLRESORCINOL
Molecular Formula: C12H18O2
Molecular Weight: 194.27
Appearance: White to pale orange or pale pink powder
Purity: 98%
CAS NO.: 136-77-6
EINECS No.: 205-257-4
Application: cosmetics and skin care products
Hexylresorcinol is a chemically synthesized component and a derivative of resorcinol, also called 4-hexyl resorcinol, generally abbreviated as 4-HR. Hexylresorcinol is the most well-known alkyl resorcinol Phenol derivatives are excellent inhibitors of polyphenol oxidase.In terms of whitening,they can inhibit the activity of tyrosinase and block the production of melanin. In addition,they can prevent UVA,UVB damage,and anti-wrinkle effects.Hexylresorcinol is the safest choice among alkyl resorcinol derivatives.It is safer and more effective than hydroquinone and kojic acid.It is one of the most powerful whitening ingredients.It can inhibit the activity of tyrosinase. ,Block the production of melanin.In addition,it can prevent UVA, UVB damage, and anti-wrinkle effects.In vivo experiments have confirmed that 0.5% hexylresorcinol has the same whitening effect as 2% hydroquinone within 8 weeks.
Efficacy of hexylresorcinol:
1. Strong tyrosinase inhibitor and strong peroxidase inhibitor: inhibit melanin production, acting on 6 positions of melanin production pathway;
2. Promote the synthesis of glutathione: Glutathione is very important to the skin's purification process. Ageing, external pressure, environmental pollution and other reasons cause the natural synthesis of glutathione in the body to attenuate, resulting in glutathione The peptide is at a low level, so the tyrosinase activity of melanocytes is enhanced. On the contrary, it promotes the synthesis of glutathione and makes glutathione reach a high level, which not only inhibits the synthesis of tyrosinase, but also protects cells from oxidative damage.
3. Reduce DNA damage: reduce melanin synthesis by protecting DNA;
4. Anti-glycation reaction: inhibit glycosylation and prevent the damage of glycosylation from causing skin darkening;
5. Anti-inflammatory and antibacterial: inhibit Propionibacterium acnes and other microorganisms.
Application of hexylresorcinol:
Hexyl resorcinol is used in cosmetics for whitening,anti-aging,repairing and other products.It has the functions of whitening and freckle removal and anti-oxidation.The product manifestations are emulsions, creams, essences, etc.
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