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Product Name: Pramoxine hydrochloride
Synonyms: TRONOTHANE HYDROCHLORIDE USP;4-n-Butoxyphenylg-morpholinopropyletherhydrochlorideusp;Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride (1:1);Pramoxine hydrochloride 4-n-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride;Pramoxine Hydrochloride (400 mg);PRAMOXINEHYDROCHLORIDE,USP;MORPHOLINE,4-(3-(PARA-BUTOXYPHENOXY)PROPYL)-,HYDROCHLORIDE;4-[3-(P-BUTOXYPHENOXY)PROPYL]MORPHOLINE HYDROCHLORIDE USP
CAS: 637-58-1
MF: C17H28ClNO3
MW: 329.86
EINECS: 211-293-1
Melting point: 181-183°
Place of Origin: Hubei, China
Brand Name:Golt Biotech
Purity: 99%
Appearance:White or off white crystalline powder
Product Categories:API
Packaging: 1kg/Aluminum foil bag,25kg/drum; customized
Payment Terms: Western Union /RIA bank transfer / BTC / TT / Money Gram
Mode of Transportation: By express or air or sea
Express: Fedex,UPS,DHL. TNT,EMS,EUB,HKEMS
Port: Shanghai,Tianjin,Qingdao,Guangzhou
Delivery Lead Time: Within 7 days by express,3-7 days by air,7- 45 days by sea
Product Description:
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development,pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.
Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics,paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
Product Application:
The popular itch creams Gold Bond and some forms of Calamine Lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble.
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.
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Packaging Details
Liquid:
Iron drum & plastic drum packaging
25kg per unit
170kg per unit
200kg per unit
1 ton per unit
Solid
Plastic bag & kraft paper bag & fiber drum
1kg per bag/drum
25kg per bag/drum
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Email/Skype: della@goltbiotech.com
Wickr me: goltbiotech8
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