Ethacridine lactate monohydrate Cas 6402-23-9
Specification
Items | Specification | Result |
Appearance | Yellow crystalline powder | Yellow crystalline powder |
Assay | 99.0%-101.0% | 99.8% |
PH | 5-7 | 6.3 |
Loss on drying | 4.5%-5.5% | 4.9% |
Sulfated ash | ≤0.1% | 0.06% |
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Ethacridine lactate monohydrate (chemical formula: C₁₅H₁₅N₃O·C₃H₆O₃·H₂O) is a synthetic organic compound with antiseptic, antibacterial, and mild astringent properties. It is most commonly used in clinical and topical settings for its targeted antimicrobial action against gram-positive bacteria (and some gram-negative strains) without significant systemic toxicity. Below is a concise, key overview:
Core Traits & Mechanism
Appearance: Yellowish crystalline powder or yellow needles, soluble in water (forming a pale yellow solution) and slightly soluble in alcohol.
Mechanism: Disrupts bacterial cell membranes and inhibits microbial enzyme activity, exerting bacteriostatic (growth-inhibiting) or bactericidal (killing) effects—especially effective against Staphylococcus aureus, Streptococcus spp., and other skin/mucosal pathogens. It has weak antifungal activity but no antiviral effects.
Key Uses
Topical Antiseptic: Treats skin wounds (cuts, abrasions, burns), ulcers (e.g., pressure sores), and infected dermatoses (e.g., impetigo, folliculitis) to prevent or control bacterial infection. Often used as a dilute (0.1–0.2%) aqueous solution for irrigation, cleansing, or wet dressings.
Mucosal Disinfection: Diluted solutions are used for vaginal irrigation (to treat bacterial vaginosis or postpartum infections) or as a mouth rinse (for gingivitis or oral ulcers—under medical guidance to avoid ingestion).
Obstetric/Gynecological Use: Historically used (in controlled concentrations) for cervical ripening or as an adjuvant in labor induction (due to mild uterine stimulant effects), though this application is less common today with newer agents.
Veterinary Medicine: Used to treat skin infections in animals (e.g., wound care for pets).
Formulations & Precautions
Synonyms
Also known as acrinol lactate monohydrate, ethacridine lactate hydrate, or brand names like Rivanol®.
In summary, it is a widely used topical antiseptic valued for its safety and effectiveness in managing superficial bacterial infections, particularly in wound care and mucosal hygiene.
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Contact information
Spring Zhang
Email: export@fortunachem.com
Skype: Fortunachem201304
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Tel: +86-27-59207892
Website: www.fortunachem.com
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