| Product name | Lovastatin |
| CAS No. | 75330-75-5 |
| Molecular Formula | C24H36O5 |
| Molecular Weight | 404.54 |
| Grade Standard | Cosmetic Grade |
| Purity | 99% |
Lovastatin is a hexahydronaphthyl ester isolated from aspergillus terraeus culture medium. It is an inactive lactone and becomes active only after being hydrolyzed after oral administration. It has a strong competitive inhibitory effect on HMG-COA reductase in liver. Hmg-coa reductase is a rate-limiting enzyme of de novo synthesis of cholesterol in vivo. Inhibition of this enzyme can block the transformation of HMG-COA to methylvaleric acid, significantly reduce cholesterol synthesis, enhance the expression of LDL receptor in liver, and enhance the clearance of LDL-C in plasma. Reduced cholesterol synthesis also reduced hepatic ApoB100 synthesis and thus VLDL synthesis. Clinical observation shows that this product has a good effect on reducing plasma total cholesterol and LDLC in all kinds of hypercholesterolemia caused by heterozygous familial hypercholesterolemia, polygenic hypercholesterolemia, diabetes mellitus and nephrotic syndrome.
A novel blood lipid regulator - HMG-COA (β -hydroxyl, β -methyl-glutarate monoacyl CoA) reductase inhibitor. It can significantly reduce the concentration of serum total cholesterol, which is hydrolyzed into the corresponding β -hydroxy acid, 3-hydroxy-3-methylglutaryl coenzyme A reductase after oral administration, and inhibit the synthesis of cholesterol. Clinical use for heterozygous familial hypercholesterolemia, severe and mild primary hypercholesterolemia, can also be used as dietary therapy adjuvant drugs, reduce the level of high cholesterol and low density protein cholesterol.
Packaging & Shipping
| Quantity(Metric Tons) | 1 - 1 | 2 - 20 | >20 |
| Est. Time(days) | 10 | 25 | To be negotiated |
Company Information
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Our Services
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.
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