Product Name: O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
Synonyms: 3,3',5-triiodothyronine;3,5,3'-triiodothyronine;3',5-triiodo-l-thyronin;4-(3-iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine;5-diiodophenyl)-3-(4-(4-hydroxy-3-iodophenoxy)-l-alanin;cytomel;l-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine;l-liothyronine
CAS: 6893-02-3
MF: C15H12I3NO4
MW: 650.97
EINECS: 229-999-3
Chemical Properties Off-White Solid
Usage Thyroidic drug;Thyroid hormone
Usage One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
COA :
| Item | Specification | Result |
|
| Appearance | An odorless, almost white or buff colored powder | pass |
|
| Solubility | 1,Very slightly soluble in water | pass |
|
| 2,slightly soluble in alcohol | pass |
|
| 3,practically insoluble in most other organic solvents | pass |
|
| 4,disolves in diluted aqueous sodium hydroxide solutions | Pass |
|
| Identification | a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. | pass |
|
| b)The retention time of the major peak is confirm to the RS | pass |
|
| Loss on Drying | Not more than 4.0% | 0.46% |
|
[a]20/D
C=1 in 1M HCl/EtOH 1:4 |
+18 ~ +22o | +20.9o |
|
| Assay(HPLC) | Not less than 95.0% | 99.18% |
|
| Levothyroxine sodium | Not more than 5.0% | 0.68% |
|
| Conclusion: | Up to the Standard for Export |
China
