Sulbutiamineis a synthetic derivative of thiamine (vitamin B1). As a dimer of twomodified thiamine molecules, it is a lipophilic compound that crosses the blood-brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain.It increases memory and alertness,Sulbutiame has a very calming effect, increases stamina.
Sulbutiamine was discovered in Japan in an effort to develop more useful thiamine derivatives since it was hoped that increasing the lipophilicity of thiamine would result in better pharmacokinetic properties