| Name | 1,3,5,8-Tetrahydroxyxanthone |
| Description | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta, exhibiting antispasmodic and anti-inflammatory activities. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method and significantly inhibits the growth of Staphylococcus aureus at a dose of 200 µg/disk. |
| In vitro | The mutagenicities of naturally occurring xanthones were tested in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method. Xanthydrol, gentisein, gentisin, isogentisin, 1-hydroxy-3,7-dimethoxyxanthone, 1,3,7-trimethoxyxanthone, Desmethylbellidifolin, bellidifolin and dimethylbellidifolin were mutagenic, but unsubstituted xanthone was not mutagenic to TA100, TA98, TA97 and TA2637 with or without a metabolic activation system[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mg/mL (38.43 mM), Sonication is recommended.
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| Keywords | Xanthone | ulcerative | spasm | muscle | Inhibitor | inhibit | colon | colitis | antispasmodic | anti-inflammatory | Anti-infection | Antiinfection | Antifection | 1,3,5,8-Tetrahydroxyxanthone | 1,3,5,8Tetrahydroxyxanthone | 1,3,5,8 Tetrahydroxyxanthone |
| Inhibitors Related | Cefotaxime | Pyrolin | WAY-329738 | N-(Hydroxymethyl)nicotinamide | 3,4,5-Trimethoxybenzaldehyde | 1,3-Dithiane | Penicillin G potassium | SulfadiMethoxine sodium | Sorbic acid | A 21960 | 2-Furoic acid | α-Terpineol |
| Related Compound Libraries | Polyphenolic Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max |
United States
