Product Name | Proparacaine Hydrochloride |
CAS NO: | 5875-06-9 |
Molecular Formular | C16H27ClN2O3 |
EINECS NO | 227-541-7 |
Purity | 99% |
Appearance | powder |
Place of origin | China |
MOQ | 1KG |
COA
| Items | Standards | Results |
| Appearance | White to light yellow crystalline powder | Complies |
| Identification | It should be Nitrogen base reaction | Complies |
| By UV | Complies |
| Should display the reaction of chloride differentiated | Complies |
| Solubility | Should dissolved in water, warm ethanol and methanol, insoluble in ether and benzene, the solution is neutral to litmus | Complies |
| Melting Point | 178ºC~185ºC | 180.3~182.1ºC |
| Loss on Drying | ≤ 0.50% | 0.14% |
| Residue on Ignition | ≤ 0.15% | 0.03% |
| Residual Solvents | DMF: ≤880ppm | ND |
| Ethanol: ≤5000ppm | ND |
| Acetone: ≤5000ppm | ND |
| Isopropanol: ≤5000ppm | ND |
| Toluene: ≤890ppm | ND |
| Methanol: ≤3000ppm | ND |
| Related Substances | If the impurities are detected, then the total amount of the impurities should be not more than 2.0%. | Complies |
| Assay (on the anhydrous basis) | 97.0%~103.0% | 99.67% |
| Reference Standard | USP35 Standard |
| Conclusion | The product complied to USP35 standard. |
| Storage | Preserve in tight,light-resistant containers in a cool place |
Description
Proparacaine HCl is a local topical eye anesthetic important for use during and after eye surgery such as laser eye treatments.
Anesthesia, local-Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure , removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy.
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
| Anesthetic / Pain Killer |
| Tetracaine Base | 94-24-6 | Prilocaine hydrochloride | 1786-81-8 |
| Tetracaine hydrochloride | 136-47-0 | Proparacaine hydrochloride | 5875/6/9 |
| Lidocaine hydrochloride | 73-78-9 | Pramoxine hydrochloride | 637-58-1 |
| Linocaine Base | 137-58-6 | Procainamide hydrochloride | 614-39-1 |
| Benzocaine hydrochloride | 23239-88-5 | Ropivacaine hydrochloride | 98717-15-8 |
| Benzocaine Base | 94-09-7 | Articaine hydrochloride | 23964-57-0 |
| Procaine | 59-46-1 | Bupivacaine | 2180-92-9 |
| Procaine hydrochloride | 1951/5/8 | Mepivacaine hydrochloride/Carbocaine | 1722-62-9 |
| Prilocaine | 721-50-6 | dibucaine hydrochloride | 61-12-1 |
Usage
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics. Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
Application
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
Contact Methods:
Contact person: Rebecca Lee
Email: rebecca@tgybio.com/sales02@tgybio.com
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Skype: +86 188 2921 5606 /+ 86 188 0296 2783
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