Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price
| Isotretinoin Chemical Properties |
| Melting point | 172-175 °C(lit.) |
| Boiling point | 381.66°C (rough estimate) |
| density | 1.0597 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | −20°C |
| solubility | Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions. |
| pka | 4.76±0.33(Predicted) |
| form | Fine Crystalline Powder |
| color | Yellow-orange to orange |
| Water Solubility | insoluble |
| λmax | 354nm(EtOH)(lit.) |
| Merck | 14,5228 |
| Stability: | Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | SHGAZHPCJJPHSC-YCNIQYBTSA-N |
| CAS DataBase Reference | 4759-48-2(CAS DataBase Reference) |
| EPA Substance Registry System | Isotretinoin (4759-48-2) |
Use of Isotretinoin
Isotretinoin Descrption
Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.
Function:
Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy.
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