Camostat mesilate NEW

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Min. Order1g
Purity99.5%
Cas No59721-29-8
Supply Ability10kg/month
Update time2026-06-18

Wuhan Fortuna Chemical Co., Ltd

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Chemical Properties

Product Name	Camostat mesilate
CAS No	59721-29-8
EC-No	694-565-6
Min. Order	1g
Purity	99.5%
Supply Ability	10kg/month
Release date	2026/06/18

Specification

Items	Specifications	Results
Appearance	Whit to off-white powder	Off-white powder
Purity	≥99.5%	99.92%
Identification	The retention time of the test product was consistent with that of the control product in the HPLC.	Conforms
Loss on drying	≤2.0%	0.14%
Maximum single impurity	≤0.1%	0.07%
Residue on ignition	≤0.2%	0
Conclusion	This product complies with the specifications.

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Camostat mesilate (or camostat mesylate) is a synthetic, orally administered protease inhibitor drug. In simpler terms, it works by blocking the activity of specific enzymes that cut proteins, a process known as proteolysis.

Mechanism of Action: How It Works

Its primary mechanism is inhibiting key serine proteases, most notably:

Transmembrane protease, serine 2 (TMPRSS2): This enzyme is present on the surface of cells in the respiratory tract, pancreas, and other organs. It plays a crucial role in priming the spike protein of certain viruses, like SARS-CoV-2 (the virus that causes COVID-19) and influenza, allowing the virus to fuse with and enter human cells. By blocking TMPRSS2, camostat mesilate can potentially prevent viral entry.
Trypsin: It is a powerful digestive enzyme produced by the pancreas.

Primary Medical Uses

Treatment of Chronic Pancreatitis and Pancreatic Pain: This is its most well-established and approved use (particularly in Japan and South Korea). By inhibiting trypsin, it reduces the auto-digestive processes and inflammation in the pancreas, which helps alleviate pain and other symptoms.
Investigated for Viral Infections: Due to its inhibition of TMPRSS2, it has been extensively studied as a repurposed drug for COVID-19. Early in vitro (lab-based) studies showed promise in blocking SARS-CoV-2 entry, but clinical trial results in humans have been mixed, showing modest or inconclusive benefits. Research for other TMPRSS2-dependent viruses is ongoing.

Key Characteristics

Brand Name: Foipan® (in Japan).
Prodrug: It is administered as an inactive prodrug. After ingestion, it is metabolized in the body into its active form, 4-(4-guanidinobenzoyloxy)phenylacetic acid (GBPA).

In summary, Camostat mesilate is a repurposed protease inhibitor drug primarily used for pancreatic inflammation, with significant research interest as a potential antiviral agent for respiratory viruses like SARS-CoV-2.

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