Prednisolone

Prednisolone is also known as hydroprednisone, chloroprednisone, prednisolone, dehydrocortisone, bailite, prednisolone acetate. The acetate is white or almost white crystalline powder, odorless and bitter. Almost insoluble in water, slightly soluble in ethanol or chloroform. It belongs to adrenocortical hormone and corticotropin. It is a medium effective glucocorticoid. Its curative effect is similar to that of prednisone, its anti-inflammatory effect is stronger, and its water and salt metabolism is weak. This product is a hydroxyl compound (hydroxyl at 11 position). It has good curative effect in local application, such as skin disease and eye disease. Because it is directly effective in local area, it is also suitable for patients with liver insufficiency. Prednisolone is mainly used in allergic and inflammatory diseases. Because this product * s sodium retention is weak, it is not necessary to replace the adrenocortical function. Adrenal cortex hyperfunction, hypertension, atherosclerosis, heart failure, diabetes, mental illness, epilepsy, postoperative patients, and gastric, duodenal ulcer, intestinal diseases or chronic malnutrition should be avoided. Do not use this kind of medicine for general infection. When acute infection is poisoned, it is necessary to cooperate with sufficient amount of effective antibiotics. For severe TB, we should combine sufficient antituberculous drugs and reduce and stop them in time.