Nilotinib

Tasigna is a new kind of targeted tumor therapy drug, which belongs to tyrosine kinase inhibitor. It is used to treat patients with chronic myeloid leukemia (CML) resistant to imatinib, and has significant curative effect. Gleevec is a preferred drug developed by Novartis for the treatment of chronic myeloid leukemia (CML).

1. Treatment of newly diagnosed Philadelphia chromosome positive adult chronic myeloid leukemia in chronic phase.

2. Treatment of Philadelphia chromosome positive chronic myeloid leukemia in blastic phase and accelerated phase.

3. Treat chronic granulocyte leukemia in chronic stage which has been treated with interferon.

4. Children with chronic myeloid leukemia who relapsed after myelosuppression or failed to respond to interferon therapy.

5. Treatment of kit (CD117) positive inoperable or metastatic malignant gastrointestinal stromal tumors.