Pomalidomide

CAS: 19171-19-8

MF: C13H11N3O4

MW: 273.24

EINECS: 805-902-5

Melting point 318.5 - 320.5°

Boiling point 582.9±45.0 °C(Predicted)

density 1.570±0.06 g/cm3(Predicted)

storage temp. 2-8°C

Uses：

Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.

Pomalidomide is a second generation immunomodulator, TNF-α inhibitor, and thalidomide analog. An inhibitor of LPS-induced TNFαrelease.

Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM