CAS: | 58-33-3 |
MF: | C17H21ClN2S |
MW: | 320.88 |
EINECS: | 200-375-2 |
Product Categories: | Inhibitors;API;Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;COLACE;Sulfur & Selenium Compounds;Histamine receptor |
Mol File: | 58-33-3.mol |
Promethazine (PM) ((RS)-N, N-dimethyl-1-(10H-phenothiazine-10-yl)propan-2-amine hydrochloride) is a phenothiazine derivative. It is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication and can also have strong sedative effects[1]. Promethazine affects ligand gated ion channels such as purinergic P2 or cholinergic ACh receptors and voltage dependent ion channels such as sodium, calcium, or potassium channels.