Valaciclovir

Product Name: Valaciclovir

CAS: 124832-26-4

MF: C13H20N6O4

MW: 324.34

EINECS: 1312995-182-4

Purpose

Used as an antiviral drug for herpes viral diseases

Pharmacological action

Valacyclovir is a guanine analogue antiviral drug, used in the treatment of herpes simplex and herpes zoster infections clinically. This product is a prodrug of acyclovir, which is quickly absorbed after oral administration and quickly converted into acyclovir in the body. Its antiviral effect is exerted by acyclovir. After acyclovir enters herpes infected cells, it competes with deoxynucleosides for viral thymidine kinase or cell kinase. The drug is phosphorylated into activated acyclovir triphosphate, which acts as a substrate for virus replication and deoxyguanine. The triphosphate competes with the viral DNA polymerase, thereby inhibiting the synthesis of viral DNA and exhibiting antiviral effects.