Specification
| Appearance | White crystal powder |
| PH value(50g/l solution，25℃)% | 4.0-5.0 |
| Heavy metals (as Pb) % | ≤ 0.001 |
| Fe,% | ≤ 0.001 |
Assay | ≥98.0% |
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EDTA-K2·2H2O (Ethylenediaminetetraacetic acid dipotassium salt dihydrate) is a highly effective chemical anticoagulant widely used in medical and laboratory settings.
Structurally, it acts as a powerful chelating agent. Its primary mechanism involves binding to calcium ions (Ca²⁺) in the blood to form stable complexes. Since calcium is an essential co-factor for the blood clotting cascade, removing it effectively prevents the blood sample from coagulating.
Here are its primary uses and key selling points:
Primary Uses
Complete Blood Count (CBC): It is the gold standard anticoagulant for routine hematology tests, including red blood cell, white blood cell, and platelet counts.
Glycated Hemoglobin (HbA1c) Testing: Used to assess average blood sugar levels over the past 2-3 months for diabetes monitoring.
Blood Typing & Cross-matching: Maintains the integrity of red blood cells for immunoserological analysis.
Molecular Biology: Frequently used in DNA extraction and PCR processes where preserving nucleic acid integrity is critical.
Key Selling Points
Superior Cell Morphology Preservation: Unlike other anticoagulants (such as heparin or oxalates), EDTA-K2 has minimal impact on the shape and volume of blood cells. This makes it exceptionally reliable for microscopic examinations and automated cell analyzers.
Excellent Solubility & Rapid Action: Compared to its sodium counterpart (EDTA-Na2), the dipotassium salt has significantly higher solubility. This allows it to dissolve quickly and completely into the blood sample upon collection, ensuring immediate and uniform anticoagulation.
Dry Coating Compatibility: It is commonly applied as a spray-dried powder coating inside vacuum blood collection tubes. This dry format prevents sample dilution and osmotic interference, which guarantees highly precise cell analysis results.
Effective Platelet Protection: It effectively inhibits platelet aggregation, making it the preferred choice for accurate platelet counting.
In summary, EDTA-K2·2H2O is the industry-standard choice for hematology because it perfectly balances rapid anticoagulation with the exceptional preservation of blood cell structure.
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