Details :
Product Name: 6-Paradol
CAS: 27113-22-0
MF: C17H26O3
MW: 278.38654
EINECS: 248-228-1
1. Specification:
Product name: 6-Paradol
CAS: 27113-22-0
Purity: 99%
Appearance: Powder
Item | Specification | Results |
Physical Property |
Appearance | White Powder | Conforms |
Odor | Characteristic | Conforms |
General Analysis |
Identification Assay (Test by HPLC) Loss on Drying | Identical to sample 99% - 101% ≤1.0% | Conforms 99.88% 0.39% |
Specific Rotation | +20.0 ~+22.0° | Conforms |
Ash | ≤3.0% | 0.68% |
Contaminants |
Lead (Pb) | ≤3.0mg/kg | 2.2 |
Arsenic (As) | ≤2.0mg/kg | 1.6 |
Cadmium (Cd) | ≤1.0mg/kg | 0.5 |
Mercury (Hg) | ≤0.1mg/kg | 0.06 |
Microbiological |
Total Plate Count | ≤1000cfu/g | Conforms |
Yeast&Mold | ≤100cfu/g | Conforms |
E.Coli. | Negative | Conforms |
Salmonella | Negative | Conforms |
2. Introduction:
Paradol is the active flavor constituent of the seeds of Guinea pepper (Aframomum melegueta or grains of paradise).It is also found in ginger. Paradol has been found to have antioxidant and antitumor promoting effects in a mouse model.
It is used in flavors as an essential oil to give spiciness.
3. Application:
Used in medicine, health products, food, beverage, cosmetics, biological and chemical reagents and other industries.
4. Health Benefits /Uses:
Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.
Paradol induces apoptosis in an oral squamous carcinoma cell line, KB, in a dose-dependent manner. Paradol induces apoptosis through a caspase-3-dependent mechanism.
China
