Description
Flubendazole is an anthelmintic. It is used by veterinarians for protection against internal parasites and worms in dogs and cats. It is also available for human use to treat worm infections.
Flubendazole is a synthetic anthelmintic belonging to the benzimidazole carbamates which acts by inhibiting the microtubular assembly in absorptive cells of nematodes. It acts by binding to tubulin, the dimeric subunit protein of the microtubules. It inhibits microtubular assembly in absorptive cells: i.e. of intestinal cells of nematodes. This is shown by disappearance of cytoplasmic microtubules, accumulation of secretory granules in the cytoplasm due to a block in their transport, leading to an impaired coating of the cellular membrane and a decreased digestion and absorption of nutrients. Irreversible lytic degeneration of the cell, due to the accumulation of secretory substances (hydrolytic and proteolytic enzymes), results in the death of the parasite.
Flubendazole is a broad-spectrum anthelminthic agent effective against endoparasites such as gastro-intestinal ascarids, hookworms, whipworms found in dogs, and active a range of gastrointestinal parasites in pigs and poultry such as roundworms, and tapeworms, Ascaris suum (large roundworm), gapeworms, Hyostrongylus rubidus (red stomach worm), Oesophagostomum dentatum (nodular worm), Trichuris suis (whip worm), Strongyloides ransomi (adult), Metastrongylus apri (lungworm).Flubendazole is ovicidal.
Function
Flubendazole is a new broad-spectrum and highly effective anthelmintic drug; the mechanism of action is to cause the parasite's digestive tract endothelial cells to disintegrate and dissolve the cells to die. It is clinically used for the treatment of echinococcosis, cysticercosis, mites, whipworms, hookworms, mites, faecalis, onchocerciasis, clonorchiasis, sericulture, and heteromorpha. It is also effective for hook and sputum skin larvae. It is also quite effective for rickets. Commonly used in the treatment of single infections and mixed infections of parasites.
Specification
Items | Standard |
Appearance | White or almost white powders |
Identification(IR) | Complies with spectrum of flubendazol CRS |
Total impurities | ≤1.5% |
Impurity A | ≤0.25% |
Impurity B | ≤0.25% |
Impurity C | ≤0.25% |
Impurity D | ≤0.25% |
Impurity E | ≤0.25% |
Impurity F | ≤0.5% |
Impurity G | ≤0.25% |
Any other impurity | ≤0.10% |
Loss on drying | ≤0.5% |
Sulphated ash | ≤0.1% |
Methanol | ≤3000ppm |
Benzene | ≤2ppm |
Assay | 99.0%~101.0% calculated on the dry basis |
Packaging & Shipping
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1. quality
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2. price
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3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service;
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
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