Methanesulfonato(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl）palladium(II) / XPhos Pd G3

1445085-55-1  

XPhos Pd G3

Synonym: (2-Dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate, 

XPhos-G3-Palladacycle, 

XPhos-Pd-G3

CAS Number: 1445085-55-1

Formula: C46H62NO3PPdS

Formula Weight: 846.45 g/mol

Appearance (Color) White to Grey and Faint Beige to Beige powder

Caution : air sensitive 

shelf life :12 month 

Supplier: LPBchem-Benjamin

assay  95%

mp  146-151 °C (decomposition)

ISO9001 Manufacturer 

Standard laboratory 

ligands catalysts synthesis compounds

Related Categories

Buchwald 3rd Generation Palladacycles, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling,

Homogeneous Pd Catalysts, Palladium Catalysts

General description

XPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XPhos Pd G3 is an excellent reagent for Suzuki cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Application

XPhos Pd G3 may be used in the following reactions: 

1.Cyanation reaction of heterocyclic halides.

2 Coupling of heteroaryl chlorides with polyfluoroaryl zinc reagents.

3 Coupling of 2,6-difluorophenylboronic acid with (hetero)aryl chlorides.