1470372-59-8
BrettPhos PdG3
Synonym: [(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate methanesulfonate
CAS Number: 1470372-59-8
Formula: C48H66NO5PPdS
Formula Weight: 906.50 g/mol
Appearance (Color) Faint Green to Very Dark Green to Very
Dark Brown
assay 98%
mp 150-193 °C (decomposition)
Caution : air sensitive
shelf life :12 month
Supplier: LPBchem-Benjamin
ISO9001 Manufacturer
Standard laboratory
ligands catalysts synthesis compounds
pharmceutical compounds OLED intermediates palladium catalysts
Related Categories
Amines, Buchwald 3rd Generation Palladacycles, Buchwald Ligands and Complexes, Building Blocks, C20 to C30+,C22 to C40+, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling, Ethers, Nitrogen Compounds - Organic Building Blocks, Organic Building Blocks, Oxygen Compounds
General description
BrettPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. BrettPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
Application
BrettPhos Pd G3 may be used for the C-N coupling reaction between monosubstituted ureas and 1,2 dihaloaromatic system to form benzimidazolones.
It may be used in the synthesis of following compounds:
- [Pd(cinnamyl)(BrettPhos)]OTf by reacting with [(cinnamyl)PdCl]2 and AgOTf.
-[Pd(crotyl)(BrettPhos)]OTf by reacting with [(crotyl)PdCl]2 and AgOTf.
-[Pd(allyl)(BrettPhos)]OTf by reacting with [(allyl)PdCl]2 and AgOTf.
- Pd(allyl)(BrettPhos)Cl by reacting with [(allyl)PdCl]2.
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