Melting point 172-175 °C(lit.)
Boiling point 381.66°C (rough estimate)
density 1.0597 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. −20°C
solubility Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka 4.76±0.33(Predicted)
form Fine Crystalline Powder
color Yellow-orange to orange
Water Solubility insoluble
Chemical Properties Yellow-Orange Crystalline Powder
Originator Accutane,Roche
Uses 5HT1a receptor agonist, anxiolytic
Uses isotretinoin is a retinoid derivative with improved bioavailability and percutaneous absorption for acne treatment products.
Uses Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.
China
