Pasiniazid

$ 17.00 /1g

Career Henan Chemica Co

VIP6Y

China

Enterprise Verified

Business Bank account Basic Contact Infomation Business Address Manufacturer

Chemical Properties

Pasiniazid Basic information

Product Name:	Pasiniazid
Synonyms:	isonicotinic acid hydrazide 4-aminosalicylate;ISONICOTINIC ACID HYDRAZIDE P-AMINOSALICYLATE SALT;PASINIAZID;isonicotinicacidhydrazidep-*aminosalicylate;PASINIAZIDISONIAZID AMINOSALICYLATE UV;Dipasic;Fintozid;Nidrapas
CAS:	2066-89-9
MF:	C13H14N4O4
MW:	290.27
EINECS:	218-183-2
Product Categories:	Pharmaceutical Intermediates
Mol File:	2066-89-9.mol

Pasiniazid Chemical Properties

Melting point	142-144°
form	neat

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

Pasiniazid Usage And Synthesis

Originator	Pasinazid, Yick-Vic Chemicals
Uses	antibacterial (tuberculostatic)
Manufacturing Process	10 parts by weight of isonicotinoyl hydrazine was dissolved in 200 by volume of methanol by stirring at 60°C. Then 11.2 parts 4-aminosalycylic acid was added at 60°C. On cooling a salt of both compounds crystallized as yellow prisms with MP: 135°-140°C (decomposed). Isonicotinic acid hydrazide compound with 4-aminosalicylic acid may be prepared from the same components by using 750 parts of water by volume as a solvent. 10 parts 4-aminosalicylic acid was dissolved in 600 volume parts of water containing 39 parts by volume 2 N ammonium hydroxide. 9 parts by weight isonicotinoyl hydrazide was added and the mixture was heated to 30°C. The solution was acidified with 49 parts by volume of 2 N acetic acid. On cooling isonicotinic acid hydrazide compound with 4-amino-salicylic acid crystallized, which decomposed at 135°-140°C. The yield was almost quantitative
Therapeutic Function	Antitubercular

Pasiniazid Preparation Products And Raw materials

Raw materials

4-Aminosalicylic acid-->Isoniazid

Company Profile Introduction