| CAS: | 6001-64-5 |
| MF: | C8H16Cl6O3 |
| MW: | 372.93 |
| EINECS: | 611-927-0 |
| Product Categories: | Miscellaneous |
| Mol File: | 6001-64-5.mol |
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| 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties |
| Melting point | 77-79 °C(lit.) |
| Boiling point | 173-175 °C |
| Fp | 100 °C |
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent). |
| form | Crystalline Powder, Crystals and/or Chunks |
| color | White to almost white |
| Water Solubility | Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water. |
| Merck | 14,2129 |
| BRN | 878167 |
| Stability: | Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents. |
| LogP | 2.074 (est) |
| CAS DataBase Reference | 6001-64-5 |
| 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Usage And Synthesis |
| Chemical Properties | white crystalline solid |
| Uses | 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility. |
| Uses | Pharmaceutic aid (antimicrobial agent). |
| Uses | 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal. |
| Brand name | Chloretone (Parke-Davis). |
| General Description | 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal. |
| Biochem/physiol Actions | Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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